CHLAMYDIA TRACHOMATIS RECOMBINANT MOMP ENCAPSULATED IN PLGA NANOPARTICLES TRIGGERS PRIMARILY T HELPER 1 CELLULAR AND ANTIBODY IMMUNE RESPONSES IN MICE: A DESIRABLE CANDIDATE NANOVACCINE

Chlamydia trachomatis recombinant MOMP encapsulated in PLGA nanoparticles triggers primarily T helper 1 cellular and antibody immune responses in mice: a desirable candidate nanovaccine

Stacie J Fairley, Shree R Singh, Abebayehu N Yilma, Alain B Waffo, Praseetha Subbarayan, Saurabh Dixit, Murtada A Taha, Chino D Cambridge, Vida A Dennis Center for NanoBiotechnology Research, Alabama State University, Montgomery, AL, USA Abstract: We recently demonstrated by in vitro experiments that PLGA (poly D, L-lactide-co-glycolide) potentiate

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Heroin and its metabolites: relevance to heroin use disorder

Abstract Heroin is an opioid agonist commonly abused for its rewarding effects.Since its synthesis at the end of the nineteenth century, its popularity as a recreational drug has ebbed and flowed.In the last three decades, heroin use has increased again, and yet the pharmacology of heroin is still poorly understood.After entering the body, heroin i

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Glucose-6-phosphate-dehydrogenase on old peroxisomes maintains self-renewal of epithelial stem cells after asymmetric cell division

Abstract Selective inheritance of sub-cellular components has emerged as a mechanism guiding stem cell fate after asymmetric cell divisions.Peroxisomes play a crucial role in multiple metabolic processes such as fatty acid metabolism and reactive oxygen species detoxification, but the apportioning of peroxisomes during stem cell division remains un

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